A ranar 13 ga Fabrairu, 2026, Cibiyar Kimanta Magunguna (CDE) ta Hukumar Kayayyakin Lafiya ta Kasa ta kasar Sin ta sanar da cewa an sanya allunan GFH375 a cikin Tsarin Maganin Farko don magance marasa lafiya da ke fama da cutar kansar huhu ta KRAS G12D-mutant non-smated cell lung cancer (NSCLC) wadanda suka sami akalla magani daya a baya.
Fasa Dokar Manufar "Undruggable"
Masana kiwon lafiya sun taɓa ɗaukar maye gurbin KRAS a matsayin wani abu da ba za a iya maye gurbinsa ba. Duk da haka, tare da ci gaban binciken kimiyya, ana shawo kan wannan ƙalubalen a hankali. KRAS G12D yana ɗaya daga cikin nau'ikan maye gurbin KRAS da aka fi gani, wanda aka saba gani a cikin adenocarcinoma na pancreas ductal (PDAC), ciwon huhu na ƙananan ƙwayoyin halitta (NSCLC), da ciwon daji na hanji.
Bayanan Asibiti Masu Ƙarfafawa: GFH375 Yana Nuna Ƙarfin Ayyukan Kariya Daga Ciwon Ƙari
Bayanan asibiti daga gwajin Phase I na GFH375 a cikin marasa lafiya da ke fama da ciwace-ciwacen KRAS G12D masu ƙarfi, wanda aka gabatar a taron shekara-shekara na American Society of Clinical Oncology (ASCO) na 2025, ya ba da sakamako mai ƙarfafa gwiwa. Bayanan sun nuna kyakkyawan samuwa ta baki da kuma aikin hana ciwace-ciwacen da aka zaɓa sosai na GFH375. Ya zuwa ranar yanke bayanai, an yi wa marasa lafiya 62 da ke fama da ciwace-ciwacen KRAS G12D masu ƙarfi da aka riga aka yi wa magani a baya gwajin Phase I na GFH375 na monotherapy.
Tawagar Ma'aikata Masu Amfani: Inganci Mai Muhimmanci Musamman
Daga cikin marasa lafiya 49 da ake shan maganin 400mg ko 600mg a baki a kowace rana, bayanan ingancin maganin sun burge sosai:
Jimlar Amsar Manufofin da Aka Yi Amfani da su (ORR): A cikin marasa lafiya 43 da aka kimanta, ORR ya kai kashi 42%, kuma Matsayin Kula da Cututtuka (DCR) ya kai kashi 91%.
Marasa lafiya na Pancreatic Ductal Adenocarcinoma (PDAC): Daga cikin marasa lafiya 23 da aka kimanta a PDAC, ORR ya kasance 52%, kuma DCR ya kai 100%.
Marasa lafiya da ke fama da cutar kansar huhu ta ƙananan ƙwayoyin halitta (NSCLC): Daga cikin marasa lafiya 12 da aka kimanta a NSCLC, ORR ya kasance 42%, kuma DCR ya kasance 83%.
Duk Tawagar Allurai: Faɗaɗa da Muhimman Ayyuka
A cikin marasa lafiya 52 da suka kammala aƙalla kimantawar ƙari ɗaya bayan magani, ORR a cikin dukkan rukunin allurai ya kasance 38%, tare da DCR na 90%. Abin lura shi ne, marasa lafiya 38 sun sami raguwar raunukan da aka yi niyya, kuma marasa lafiya 20 sun sami wani ɓangare na amsawa. Waɗannan bayanan farko sun nuna cewa GFH375 yana nuna babban aikin hana ciwace-ciwace a cikin marasa lafiya da ke da ciwon daji kamar PDAC da NSCLC, gami da waɗanda suka ci gaba bayan layuka da yawa na magani.
Fuskantar irin waɗannan ci gaban kiwon lafiya na zamani, zaɓar cibiyar likitanci da za ta iya samar da zaɓuɓɓukan magani na zamani da kuma cikakkun ayyuka yana da matuƙar muhimmanci. Sashen Duniya na Asibitin Oncology na Yankin Kudu na Beijing ya himmatu wajen bayar da ayyukan gano cutar kansa da kuma kula da marasa lafiya na cikin gida da na ƙasashen waje. Muna ci gaba da sanar da sabbin abubuwan da suka faru a binciken cutar kansa na duniya kuma mun himmatu wajen kawo magunguna masu inganci kamar GFH375 ga marasa lafiya da ke cikin buƙata cikin sauri.
Fa'idodinmu sun haɗa da:
Mafita Mafita ta Lafiya: Muna bin ƙa'idodin ƙasashen duniya, muna mai da hankali kan kuma gabatar da hanyoyin magani na zamani waɗanda suka haɗa da GFH375, muna ba da damar warkewa ga marasa lafiya da ke fama da maye gurbi na KRAS G12D.
Ƙungiyar Ƙwararrun Ma'aikata Masu Nazari Daban-daban: Muna haɗa manyan ƙwararrun masana ilimin cututtukan daji na cikin gida waɗanda ke yin aiki tare a cikin shawarwari daban-daban don ƙirƙirar tsare-tsaren magani na musamman da daidai ga kowane majiyyaci.
Ka'idojin Sabis na Ƙasashen Duniya: Tun daga shawarwari, tsara alƙawari, ayyukan fassara zuwa ga dukkan tsarin magani, muna ba da sadarwa mai kyau da kuma kulawa, muna tabbatar da jin daɗin da kuma kwantar da hankali ga marasa lafiya na ƙasashen waje da iyalansu.
Cikakken Tallafin Marasa Lafiya: Muna ƙoƙarin samun ƙwarewa ba kawai a fannin magani ba, har ma da mai da hankali kan lafiyar lafiyar marasa lafiya da ingancin rayuwa, muna ba da tallafi da kulawa ga marasa lafiya.
Tuntube Mu Yanzu Don Bincika Sabuwar Fata Don Magani
Idan kai ko wani ɗan uwa an gano kana da cutar kansar huhu ta KRAS G12D-mutant non-smatant cell cancer ko wasu ciwace-ciwacen da ba su da ƙarfi kuma ba ka da isasshen magani ga hanyoyin magani da ake da su, tuntuɓi Sashen Ƙasa da Ƙasa na Asibitin Oncology na Yankin Kudu na Beijing. Ƙungiyar ƙwararrunmu za ta ba ka sabbin bayanai na likita da shawarwarin gano cutar da magani na musamman.
Don Allah a tuntube mu ta hanyoyi masu zuwa:
Waya: 400-880-3716
WeChat: 17801183037
Email: 100085_010@163.com 或 myimmnet@163.com
Kada ku bari shingen nesa ko harshe su zama cikas a cikin neman magani mai zurfi. Sashen Duniya na Asibitin Oncology na Yankin Kudu na Beijing yana nan don tsayawa tare da ku a yaƙi da cutar kansa.
Lokacin Saƙo: Fabrairu-25-2026